In September, the Fourth Circuit Court of Appeals issued a significant decision affecting the hemp industry on the federal level. There has been an open question for some time regarding the legality of certain cannabinoids that do not naturally occur in the cannabis plant but can be created from hemp products. THC-O (tetrahydrocannabinol acetate) is an example of such a compound. State and federal criminal law both ban “synthetic THC.” What exactly counts as “synthetic” THC? I wrote a bit about this ambiguity in the law before, but Anderson v. Diamondback Investment Group, LLC, ___ F.4th ___; 2024 WL 4031401 (4th Cir. 2024), provides some of the first guidance on the issue in the age of legal hemp. Read on for the details.